Oligodeoxynucleotides containing 3′-allylether, 3′-allylsulfide and their saturated derivatives as phosphate mimics

Article abstract of DOI:10.1016/0040-4039(94)85210-3

A series of novel thymidine-thymidine dimers containing 3′-allylether, 3′-allylsulfide connections and their saturated derivatives have been prepared and incorporated into oligodeoxynucleotides (ODNs). The 3′-allylether analog results in only a modest des