Tetrahedron Asymmetry p. 1111 - 1118 (1994)
Update date:2022-08-03
Topics: Lipase Hydrolysis Enantiomers Resolution Racemic mixture
O'Hagan, David
Zaidi, Naveed A.
The resolution of tertiary alcohols using the Candida cylindracea lipase is explored.In particular strategies are deployed to limit nonenzymatic hydrolysis of the tertiary acetate substrates in buffer, such that a full range of the steric requirements and
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