Synthesis of peptide derivatives of 5-fluorouracil

DOI: 10.1016/S0040-4020(01)90395-3

Source and publish data:

Tetrahedron p. 3747 - 3760 (1994)

Update date:2022-08-03

Topics: -Synthesis -Experimental -Reaction conditions

Authors:

Nichifor, Marieta

Schacht, Etienne H.

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Article abstract of DOI:10.1016/S0040-4020(01)90395-3

The preparation of di-, tetra- and pentapeptides carrying 5-fluorouracil as an α-substituent of a terminal glycine moiety is described. The dipeptide compounds were synthetized by addition of ethyl glyoxylate to N-(benzyl-oxycarbonyl)-amino acid amides, s

Full text of DOI:10.1016/S0040-4020(01)90395-3

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Product name:(S)-2-{(S)-2-[2-(9H-Fluoren-9-ylmethoxycarbonylamino)-acetylamino]-3-phenyl-propionylamino}-4-methyl-pentanoic acid pentafluorophenyl ester

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