
Journal of Organic Chemistry p. 115 - 119 (1995)
Update date:2022-08-04
Topics:
Isono, Naohiro
Mori, Miwako
Total synthesis of (-)-cephalotaxine was achieved from D-(+)-proline by a short sequence of steps.The key intermediate, 1-azaspiro<4.4>nonane, was prepared from vinyl iodide, using stannyl anion generated from Me3SiSnBu3 and CsF, in good yield.
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