Total Synthesis of (-)-Cephalotaxine

DOI: 10.1021/jo00106a023

Source and publish data:

Journal of Organic Chemistry p. 115 - 119 (1995)

Update date:2022-08-04

Topics:

Authors:

Isono, Naohiro

Mori, Miwako

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo00106a023

Total synthesis of (-)-cephalotaxine was achieved from D-(+)-proline by a short sequence of steps.The key intermediate, 1-azaspiro<4.4>nonane, was prepared from vinyl iodide, using stannyl anion generated from Me3SiSnBu3 and CsF, in good yield.

Full text of DOI:10.1021/jo00106a023

Products guided by the article

Product name:(2S)-Methyl 2-((Z)-3-iodo-2-propenyl)-1-<2-(3,4-dimethoxyphenyl)ethyl>pyrrolidine-2-carboxylate

Cas No:160360-11-2

R&D Labs maybe for 160360-11-2

Guangxi Shanyun Biochemical Science and Technology Co., Ltd

Contact:+86-0772--6828887

Address:#2 Industrial Park of Luzhai County, Liuzhou, Guangxi, China
Changzhou Foreign Trade Corp

Contact:+86-519-86623222

Address:29F/D, 99 Yanling West Road, Changzhou, Jiangsu, China
Jiangsu Seed Chem Co.,Ltd.

Contact:86-513-84128750/13773795976

Address:No.48.Youyi West Road ,Rudong Development Zone,Jiangsu Province,China
Ningbo J&S Botanics Inc.

Contact:86-574-26865651

Address:529 YuanBaoShan Road, Beilun District
Zhongshan Haihong Medicine Co., Ltd.

Contact:86-0760-86925778 （0）18824993998

Address:A7 building,lianyuan road Torch Hi-tech Industrial Development Zone

Relevant to this article

On-Demand Selection of the Reaction Path from Imino Diels-Alder to Ene-Type Cyclization: Synthesis of Epiminopyrimido[4,5-b]azepines

Doi:10.1002/ejoc.201301318
(2014)
Asymmetric synthesis of the antibiotic (+)-thiamphenicol using cis-N-(p-toluenesulfinyl)aziridine 2-carboxylic acids

Doi:10.1016/S0040-4039(00)78334-1
(1994)
Synthesis of (2R,3R,4S)-2-hydroxymethylpyrrolidine-3,4-diol from (2S)-3,4-dehydroproline derivatives

Doi:10.1016/0008-6215(94)84059-8
(1994)
Catalytic enantioselective C(sp³)H functionalization: Intramolecular benzylic [1,5]-hydride shift

Doi:10.1016/j.tetlet.2014.03.089
(2014)
Molecular design for a cybotactic nematic phase

Doi:10.1039/c4tc00001c
(2014)
Crafting NPB with tetraphenylethene: A win-win strategy to create stable and efficient solid-state emitters with aggregation-induced emission feature, high hole-transporting property and efficient electroluminescence

Doi:10.1039/c4tc00145a
(2014)

Article Doi