Molecules p. 15182 - 15192 (2013)
Update date:2022-08-04
Topics:
Nisar, Muhammad
Ali, Ihsan
Shah, Muhammad Raza
Qayum, Mughal
Zia-Ul-Haq, Muhammad
Rashid, Umer
Islam, Md. Saiful
An efficient method has been developed for the synthesis of β-enaminones under solvent-free reaction conditions using PPA-SiO2 as catalyst. The reaction yields were good to excellent (up to 90%). This methodology affords high selectivity and good tolerance of a variety of different functional groups present on both aromatic and aliphatic amines. In addition, the methodology is environmentally benign and cost-effective due to absence of solvent and easy work-up.
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(2014)