Synthesis of a Highly Functionalised AB Taxane Ring System: Formation of the Eight-membered Ring by an Efficient 8-exo-tet Alkylation of an α-Sulfonyl Anion

DOI: 10.1039/c39950000085

Source and publish data:

Journal of the Chemical Society. Chemical communications p. 85 - 86 (1995)

Update date:2022-07-30

Topics: Synthesis Alkylation Efficient Anion Formation Highly functionalised

Authors:

Crich, David

Natarajan, Swaminathan

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Article abstract of DOI:10.1039/c39950000085

An efficient, scalable route to a Taxol A ring synthon has been developed; its successful elaboration to a highly functionalized AB system by means of a novel nucleophilic ring closure is described.

Full text of DOI:10.1039/c39950000085

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