Regioselective protection of the 2'-hydroxyl group of N-acyl-3',5'-O-di(t-butyl)silanediylnucleoside derivatives by use of t-BuMgCl and 2-(trimethylsilyl)ethoxymethyl chloride

DOI: 10.1016/0040-4039(95)00130-5

Source and publish data:

Tetrahedron Letters p. 1683 - 1684 (1995)

Update date:2022-08-05

Topics:

Authors:

Wada Wada

Tobe Tobe

Nagayama

Furusawa

Sekine Sekine

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Article abstract of DOI:10.1016/0040-4039(95)00130-5

Regioselective 2'-O-protection of N-protected 3',5'-O-di(t-butyl)silanediylribonucleoside derivatives with the 2-(trimethylsilyl)ethoxymethyl (SEM) group has been achieved by use of t-BuMgCl and 2-(trimethylsilyl)ethoxymethyl chloride. The former was used

Full text of DOI:10.1016/0040-4039(95)00130-5

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