Dynamic Kinetic Resolution of Racemic α-halo Acids via a Chiral Imidazolidinone Auxiliary

DOI: 10.1016/0040-4039(95)00339-E

Source and publish data:

Tetrahedron Letters p. 2559 - 2562 (1995)

Update date:2022-08-04

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Authors:

O'Meara, Jeff A.

Jung, Manfred

Durst, Tony

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Article abstract of DOI:10.1016/0040-4039(95)00339-E

A dynamic kinetic resolution is utilized to realize highly diastereoselective nucleophilic displacement of bromine in tert-butyl (4S)-1-methyl-3-(2-bromoacyl)-2-oxoimidazolidine-4-carboxylates (6a-f) by benzylamine enroute to tert-butyl (4S)-1-methyl-3-(2

Full text of DOI:10.1016/0040-4039(95)00339-E

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