Journal of Agricultural and Food Chemistry p. 2536 - 2541 (1995)
Update date:2022-08-03
Topics:
Jorba, Xavier
Gill, Iqbal
Vulfson, Evgeny N.
The feasibility of flavor peptide production has been investigated using proteases in liquid/semiliquid eutectic mixtures comprised of the substrates together with small amounts of water and alcohols (19-24percent w/w).The three functional fragments of the so-called "Delicious Octapeptide", L-Lys-Gly, L-Asp-Glu-Glu, and L-Ser-Leu-Ala, were obtained in good yields without any requirement for the regioselective side-chain protection of multifunctional amino acids.The peptides were synthesized on a preparative scale in overall yields of 29-77percent and were fully characterized.Keywords: Delicious Peptide; food peptides; flavor peptides; enzymatic peptide synthesis; eutectic mixtures; proteases; adjuvants
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