Tetrahedron Letters p. 2187 - 2190 (1999)
Update date:2022-08-03
Topics:
Challenger, Stephen
Derrick, Andrew
Mason, Clive P.
Silk, Terry V.
A four step synthesis of a chiral glutarate half ester intermediate, required for the preparation of candoxatril, has been developed from t-butyl acrylate. The key steps in this route include a stereoselective synthesis of a trisubstituted alkene and its asymmetric hydrogenation with a Ru-BINAP catalyst.
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Doi:10.1016/j.carres.2017.09.015
(2017)Doi:10.1039/c39950001419
(1995)Doi:10.1016/j.tet.2005.03.030
(2005)Doi:10.1021/ja01180a019
(1949)Doi:10.1039/jr9440000114
(1944)Doi:10.1055/s-1983-30223
(1983)
