β-Glucuronyl carbamate based pro-moieties designed for prodrugs in ADEPT

DOI: 10.1016/0040-4039(95)00049-I

Source and publish data:

Tetrahedron Letters p. 1701 - 1704 (1995)

Update date:2022-08-03

Topics:

Authors:

Leenders

Leenders, Ruben G.G.

Gerrits Gerrits

Gerrits, Kasper A. A.

Ruijtenbeek

Ruijtenbeek, Rob

Scheeren

Scheeren, Hans W.

Haisma Haisma

Haisma, Hidde J.

Boven Boven

Boven, Epie

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Article abstract of DOI:10.1016/0040-4039(95)00049-I

A number of pro-moieties 8a-e designed for prodrug preparation have been synthesized. The pro-moieties, containing a glucuronyl carbamate group linked to a spacer possessing a terminal carboxylic acid group, have been synthesized from isocyanates 6 and an

Full text of DOI:10.1016/0040-4039(95)00049-I

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Product name:(2-Isocyanato-phenyl)-acetic acid allyl ester

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