Synthetic Communications p. 2468 - 2474 (2011)
Update date:2022-08-03
Topics:
Li, Yong-Hong
Huang, Li-Hua
Liu, Hong-Min
An efficient chemoenzymatic route to S-betaxolol is reported. A strain (Rhodotorula mucilaginosa DQ832198) screened from soil was used as biocatalyst for the kinetic resolution of the key acetylated intermediates. Excellent enantiomeric excess (ee99%) was
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