Synthesis of saframycins. XI. Synthetic studies toward a total synthesis of safracin A

DOI: 10.1016/0040-4020(95)00437-D

Source and publish data:

Tetrahedron p. 8213 - 8230 (1995)

Update date:2022-08-03

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Authors:

Saito, Naoki

Harada, Shunji

Yamashita, Mihoko

Saito, Takeshi

Yamaguchi, Kentaro

Kubo, Akinori

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Article abstract of DOI:10.1016/0040-4020(95)00437-D

A synthetic strategy for the preparation of isoquinolinequinone antibiotic safracin A (1a) is outlined. Our initial strategy for the construction of the ABC ring was based on a retrosynthetic analysis. Conversion of 5 in five steps to the imide 16 was fol

Full text of DOI:10.1016/0040-4020(95)00437-D

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