Synthesis and antibacterial activity of novel oxazolidinones bearing N-hydroxyacetamidine substituent

Article abstract of DOI:10.1016/j.bmcl.2006.01.109

Novel oxazolidinone antibacterials containing N-hydroxyacetamidine moiety are synthesized with the diversity at C-5 terminus. These compounds have been evaluated against a panel of clinically relevant Gram-positive and Gram-negative pathogens. Most of the