Synthesis and Rearrangement of Potential Zinc β-lactamase Inhibitors

DOI: 10.1016/0040-4039(95)02028-N

Source and publish data:

Tetrahedron Letters p. 9313 - 9316 (1995)

Update date:2022-08-02

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Authors:

Hove, Francois Van

Vanwetswinkel, Sophie

Marchand-Brynaert, Jacqueline

Fastrez, Jacques

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Article abstract of DOI:10.1016/0040-4039(95)02028-N

On alkylation of the p-toluene sulfonic salt of benzyl 6-aminopenicillanate (6-APA) with benzyl 2-bromoacetate, the benzyl esters of N-(benzyloxycarbonylmethyl)-6-APA (1) and of N,N-di(benzyloxycarbonylmethyl)-6-APA (3) were obtained.Hydrogenolysis of 1 o

Full text of DOI:10.1016/0040-4039(95)02028-N

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