D-Xylose derived oxazolidin-2-ones as chiral auxiliaries in stereoselective acylations and halogenations

Article abstract of DOI:10.1016/S0957-4166(96)00478-8

Chiral N-acylated oxazolidin-2-ones readily available from D-xylose have been demonstrated to undergo highly diastereoselective acylation reactions via their lithium imide enolates to afford β-keto imides. These are easily purified and exhibit surprisingl