A formal synthesis of (-)-pumiliotoxin C

DOI: 10.1016/0957-4166(96)00190-5

Source and publish data:

Tetrahedron Asymmetry p. 1595 - 1596 (1996)

Update date:2022-08-02

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Authors:

Davies, Stephen G.

Bhalay, Gurdip

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Article abstract of DOI:10.1016/0957-4166(96)00190-5

An asymmetric synthesis of an advanced intermediate in the synthesis of natural (-)-pumiliotoxin C has been achieved in six steps and in 61% overall yield employing as the key step a highly diastereoselective lithium amide 1,4-conjugate addition to a dien

Full text of DOI:10.1016/0957-4166(96)00190-5

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