Cyclization of a chiral oxazolidine as a key-step for the synthesis of functionalized piperidines

DOI: 10.1016/0040-4039(96)00767-8

Source and publish data:

Tetrahedron Letters p. 4001 - 4002 (1996)

Update date:2022-07-29

Topics:

Authors:

Agami, Claude

Couty, Francois

Mathieu, Helene

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/0040-4039(96)00767-8

Bicyclic oxazolidine 6, a potential precursor for the synthesis of enantiopure piperidines and indolizidines, was synthesized from (R)-phenylglycinol. A stereoselective addition of cyanide anion on this compound afforded ultimately (2S,3S)-3-hydroxypipecolic acid 9.

Full text of DOI:10.1016/0040-4039(96)00767-8

Products guided by the article

Product name:(2R,3S)-3-Benzyloxy-1-((R)-2-hydroxy-1-phenyl-ethyl)-1,2,3,6-tetrahydro-pyridine-2-carbonitrile

Cas No:179600-36-3

R&D Labs maybe for 179600-36-3

Hangzhou Yanshan Chemical Co.,Ltd.

Contact:86-571- 87698076

Address:Room 1001, #1 Building, Zhongtian MCC, No.2 Youzhinong, Wenyi West Road, Xihu District, Hangzhou, China
Sichuan JieYao Co., Ltd.

Contact:+86-838-5655598

Address:Guanghan Nanfeng Industrial Zone
shandong lukang animal & plant drug trading co.,ltd.

Contact:15853765968

Address:floor 9, lukang ,jingying building,#173,taibai building west road,jining city,shandong,china
ShangHai Soyoung Biotechnology Inc

website:http://www.soyoungbio.com

Contact:+86-21-69893009

Address:shanghai
Arshine Pharmaceutical Co., Limited

website:http://www.cnarshine.com

Contact:0731-88503671

Address:Room 1109.Block C3, Lugu Enterprise Plaza,No.27 Wenxuan Road,Changsha National Hi-Tech Industrial Development Zone,Hunan ,P.R.China

Relevant to this article

Synthesis of the tritium labeled SCH 58261, a new non-xanthine A(2A) adenosine receptor antagonist

Doi:10.1002/(SICI)1099-1344(199608)38:8<725::AID-JLCR885>3.0.CO;2-G
(1996)
Synthesis of reagents for the one step incorporation of hydrazide functionality onto the lysine residues of proteins, and their use as linkers for carbonyl containing molecules

Doi:10.1016/S0960-894X(96)00265-X
(1996)
Synthesis and biological activity of hydrazones of o- and p-hydroxybenzoic acids. Spatial structure of 5-Bromo-2-hydroxybenzylidene-4-hydroxybenzohydrazide

Doi:10.1134/S1070363217100097
(2017)
GEMINAL SYSTEMS. COMMUNICATION 23. REACTION OF N,N-DIALKOXYAMINES WITH ELECTROPHILES

Doi:10.1007/BF00954351
(1983)
Reaction of iron dicarbonyl phosphine complexes of 2-(phenylazo)pyridines with dimethyl acetylenedicarboxylate. Synthesis and crystal structure of a 2,3,1-diazaferrole complex

Doi:10.1016/0022-328X(96)06243-2
(1996)
Doi:10.1016/S0021-9673(00)95595-X
(1974)

Article Doi