Cobalt-mediated alkylation of (4R) and (4S)-3-acetoacetyl-4-benzyloxazolidin-2-ones. Preparation of enantiopure diphenylmethyl-, 9-fluorenyl-, and (1-adamantyl)glycines

DOI: 10.1016/0040-4039(96)01322-6

Source and publish data:

Tetrahedron Letters p. 6197 - 6200 (1996)

Update date:2022-09-26

Topics:

Authors:

Galvez, Nicanor

Moreno-Manas, Marcial

Vallribera, Adelina

Molins, Elies

Cabrero, Araceli

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/0040-4039(96)01322-6

The Co(II) complexes of (4R) and (4S)-3-acetoacetyl-4-benzyloxazolidin-2-ones are alkylated diastereoselectively with diphenylmethyl, 9-fluorenyl, and 1-adamantyl bromide. The resulting products are converted into enantiopure α-substituted glycines. Similar results are obtained by alkylation of the free acetoacetyloxazolidinones under Co(II)-catalysis.

Full text of DOI:10.1016/0040-4039(96)01322-6

Products guided by the article

Product name:N-[(S)-1-Adamantan-1-yl-2-((S)-4-benzyl-2-oxo-oxazolidin-3-yl)-2-oxo-ethyl]-acetamide

Cas No:182439-68-5

R&D Labs maybe for 182439-68-5

Jiangxi Dongbang Pharmaceutical Co., Ltd.

Contact:+86-795-4433603, 4433388

Address:Fengxin Industrial Park, Fengxin County, Jiangxi Province, P.R.C
SHANGHAI ARCADIA BIOTECHNOLOGY LTD.

Contact:+86-21-61353236

Address:SUITE 901, BUILDING WENSLI, 1378 LU JIA BANG RD, SHANGAHI 200011, P.R.CHINA
Suzhou Jingye Medicine & Chemical Co., Ltd

website:http://www.jingyechem.cn

Contact:+86-512-66658588

Address:No. 88, Sanlian Street, Jinfeng Road, Suzhou New District, Jiangsu Province, P. R. China
LIAONING DMSO CHEMICALS CO.,LTD.

website:http://www.chinadmso.com

Contact:+86-427-6503033

Address:FLOOR 16, BLOCK A, FINANCIAL SQUARE, XINGLONGTAI DISTRICT, PANJIN CITY, LIAONING P.R. CHINA
Suzhou Wedo Chemicals Co., Ltd.

Contact:86 512 58100425

Address:Zonger Road, DongSha Industry Park , Zhangjiagang, Jiangsu, China

Relevant to this article

Facile synthetic entry into the 1,3-dihydro-3-methyl-3-phenyl-1,2-benziodoxole family of λ³-iodanes

Doi:10.1016/0040-4039(96)01436-0
(1996)
Enantiospecific synthesis of 8-O-methylthioswainsonine from a derivative of D-glucose

Doi:10.1016/0957-4166(96)00330-8
(1996)
Propargylic dithioacetal as an allene 1,3-dication synthon. Nickel-catalyzed cross-coupling reactions of propargylic dithioacetals with Grignard reagents

Doi:10.1021/jo961514c
(1996)
An asymmetric synthesis (-)-epibatidine

Doi:10.1016/0040-4039(96)01739-X
(1996)
Dinuclear cycloaurated complexes containing bridging (2-diphenylphosphino)phenylphosphine and (2-diethylphosphino)phenylphosphine, C₆H₄PR₂ (R = Ph, Et). Carbon-carbon bond formation by reductive elimination at a gold(II)-gold(II) center

Doi:10.1021/ja961511h
(1996)
Development of a highly sensitive and specific immunoassay for determining chrysoidine, a banned dye, in soybean milk film

Doi:10.3390/molecules16087043
(2011)

Article Doi