Cobalt-mediated alkylation of (4R) and (4S)-3-acetoacetyl-4-benzyloxazolidin-2-ones. Preparation of enantiopure diphenylmethyl-, 9-fluorenyl-, and (1-adamantyl)glycines

DOI: 10.1016/0040-4039(96)01322-6

Source and publish data:

Tetrahedron Letters p. 6197 - 6200 (1996)

Update date:2022-09-26

Topics:

Authors:

Galvez, Nicanor

Moreno-Manas, Marcial

Vallribera, Adelina

Molins, Elies

Cabrero, Araceli

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/0040-4039(96)01322-6

The Co(II) complexes of (4R) and (4S)-3-acetoacetyl-4-benzyloxazolidin-2-ones are alkylated diastereoselectively with diphenylmethyl, 9-fluorenyl, and 1-adamantyl bromide. The resulting products are converted into enantiopure α-substituted glycines. Similar results are obtained by alkylation of the free acetoacetyloxazolidinones under Co(II)-catalysis.

Full text of DOI:10.1016/0040-4039(96)01322-6

Products guided by the article

Product name:N-[(S)-1-Adamantan-1-yl-2-((S)-4-benzyl-2-oxo-oxazolidin-3-yl)-2-oxo-ethyl]-acetamide

Cas No:182439-68-5

R&D Labs maybe for 182439-68-5

ZHANGJIAGANG FREE TRADE ZONE YONG HAN INTERNATIONAL TRADING CO., LTD(expird)

Contact:86 512 57910558

Address:qianjin M road
SHANXI XINTIANYUAN PHARMACEUTICAL CO., LTD.

website:http://www.tychemical.com

Contact:0086-358-3521713 3521715

Address:No. 1 Yintong Road, Shanxi Jiaocheng Economic Development Zone, Xiajiaying Town, Jiaocheng County, Lvliang City, Shanxi Province, China
Disynthesis Chemical Technology Co. Ltd.

Contact:+86-571-88194596

Address:Dengyun road 380, Gongshu district, Hangzhou city, China
Zha Yan

Contact:+86-13914766747

Address:Floors 21&22, Jin Cheng Tower, No. 216 Middle Longpan Road, Nanjing
Evergreen Chemical Industry Ltd.

Contact:86-553-4918210

Address:6#2-602 Wanhaobailing

Relevant to this article

Facile synthetic entry into the 1,3-dihydro-3-methyl-3-phenyl-1,2-benziodoxole family of λ³-iodanes

Doi:10.1016/0040-4039(96)01436-0
(1996)
Enantiospecific synthesis of 8-O-methylthioswainsonine from a derivative of D-glucose

Doi:10.1016/0957-4166(96)00330-8
(1996)
Propargylic dithioacetal as an allene 1,3-dication synthon. Nickel-catalyzed cross-coupling reactions of propargylic dithioacetals with Grignard reagents

Doi:10.1021/jo961514c
(1996)
An asymmetric synthesis (-)-epibatidine

Doi:10.1016/0040-4039(96)01739-X
(1996)
Dinuclear cycloaurated complexes containing bridging (2-diphenylphosphino)phenylphosphine and (2-diethylphosphino)phenylphosphine, C₆H₄PR₂ (R = Ph, Et). Carbon-carbon bond formation by reductive elimination at a gold(II)-gold(II) center

Doi:10.1021/ja961511h
(1996)
Development of a highly sensitive and specific immunoassay for determining chrysoidine, a banned dye, in soybean milk film

Doi:10.3390/molecules16087043
(2011)

Article Doi