Journal of Medicinal Chemistry p. 4197 - 4210 (1996)
Update date:2022-08-02
Topics:
Patel, Dinesh V.
Young, Marian G.
Robinson, Simon P.
Hunihan, Lisa
Dean, Brenda J.
Gordon, Eric M.
The rational design, synthesis, and activity of novel, hydroxamic acid- based, collective bisubstrate analog inhibitors of farnesyl protein transferase (FPT) is described. This class of compounds differ structurally from the conventional FPT inhibitors by
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