Asymmetric strecker synthesis of the four α-quaternary 1-amino-2-methylcyclohexanecarboxylic acids

DOI: 10.1002/jlac.199619961126

Source and publish data:

Liebigs Annalen p. 1893 - 1903 (1996)

Update date:2022-07-30

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Authors:

Volk, Franz-Josef

Frahm, August Wilhelm

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Article abstract of DOI:10.1002/jlac.199619961126

The synthesis of the four 1-amino-2-methylcyclohexanecarboxylic acids 13, 14, 15, and 16 from diastereomeric mixtures of the α-amino nitriles 1-4 by successive application of conc. H₂SO₄, Pd/C H₂, and conc. HCl is describe

Full text of DOI:10.1002/jlac.199619961126

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Product name:(1S,2R)-2-Methyl-1-((S)-1-phenyl-ethylamino)-cyclohexanecarboxylic acid amide

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