Tetrahedron Letters p. 7653 - 7656 (1996)
Update date:2022-08-02
Topics:
Bennasar, M.-Lluisa
Jimenez, Juan-Miguel
Sufi, Bilal A.
Bosch, Joan
1,4-Dihydropyridines 3 resulting from the addition of the enolate derived from 1-acetylindole (1) to pyridinium salts 2 do not undergo cyclization under the usual acidic conditions, but do satisfactorily cyclize to the tetracyclic derivatives 4 by treatment with TsOH in the presence of lithium iodide.
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