Structural requirements of an external, chiral amidophosphine ligand for asymmetric reaction of an organocopper reagent

Article abstract of DOI:10.1016/0040-4039(96)01783-2

Three types of an external, chiral amide ligand, 2-6, were prepared and examination of their behavior in an asymmetric conjugate addition reaction of lithium dimethylcuprate with chalcone revealed to possibility for steric tuning to realize high selectivity.