Journal of Fluorine Chemistry p. 159 - 162 (1996)
Update date:2022-08-04
Topics:
Deprez, Pierre
Vevert, Jean-Paul
Demethylation of methylthio imidazole 1 via a Pummerer rearrangement onto the corresponding sulfoxide 2 afforded imidazole thiol 4 which was then difluoromethylated with the sodium chlorodifluoroacetate/NaI system in 71% overall yield.
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(1996)
