Resolution and assignment of the absolute stereochemistry of a trans-2,3-diarylpyrrolidine LTB4 inhibitor intermediate

DOI: 10.1016/S0957-4166(96)00512-5

Source and publish data:

Tetrahedron Asymmetry p. 185 - 186 (1997)

Update date:2022-08-04

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Authors:

Roth, Gregory P.

Emmanuel, Michel

Tong, Liang

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Article abstract of DOI:10.1016/S0957-4166(96)00512-5

1,3-Cycloaddition of an azaallyl anion with 4-methoxystyrene furnishes the corresponding racemic trans-pyrrolidine. Resolution of both enantiomers was accomplished by fractional crystallization with the inexpensive diacetone-2-keto-L-gulonic acid. The abs

Full text of DOI:10.1016/S0957-4166(96)00512-5

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Product name:2-[(2R,3S)-3-(4-Methoxy-phenyl)-pyrrolidin-2-yl]-pyridine

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