Synthesis of β-amino esters by the conjugate addition of nitrogen nucleophiles to α,β-unsaturated esters having chiral p-tolylsulfinyl groups

Article abstract of DOI:10.1246/cl.1997.375

The conjugate addition of nitrogen nucleophiles to t-butyl (E)-2-(p-tolylsulfinyl)cinnamates (1) afforded the corresponding chiral β-amino esters, which are important building blocks for synthesis of biologically active polyamine alkaloids. The diastereos