A high-yield synthesis of deoxy-2-fluoroinosine and its incorporation into oligonucleotides

DOI: 10.1016/S0040-4039(97)00540-6

Source and publish data:

Tetrahedron Letters p. 2989 - 2992 (1997)

Update date:2022-08-05

Topics:

Authors:

Adib, Abdennaji

Potier, Pierre F.

Doronina, Svetlana

Huc, Ivan

Behr, Jean-Paul

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(97)00540-6

An improved synthesis of the deoxy-2-fluoroinosine nucleoside is described, that makes use of mild fluorination (polyvinylpyridinium polyhydrogenfluoride) and O-silyl deprotection (triethylamine trihydrofluoride) reactions. The derived 5'-dimethoxytrityl-

Full text of DOI:10.1016/S0040-4039(97)00540-6

Products guided by the article

Product name:((2R,3S,5R)-3-(tert-Butyl-dimethyl-silanyloxy)-5-{2-fluoro-6-[2-(4-nitro-phenyl)-ethoxy]-purin-9-yl}-tetrahydro-furan-2-yl)-methanol

Cas No:190506-34-4

R&D Labs maybe for 190506-34-4

Hangzhou Pharma & Chem Co.,Ltd.

Contact:+86-571-87040515

Address:No,139Qingchun Rd
Changzhou Ansciep Chemical Co.,Ltd.

Contact:+86 519 8630 5871

Address:A-710 Boan International, 8 East Guangdian Road,Wujin,Changzhou
Luna Chemicals Co.,Ltd.

Contact:+86-570-4336358

Address:No.87 Building,Tianqian,Sidu Town
Shanxi Tongji Pharmaceuticals Co., Ltd.

Contact:+86-359-3024784

Address:Xikuang South Road, Ruicheng County , Shanxi
JenKem Technology Co., Ltd.

Contact:86-10-62983737; +86-10-51287608

Address:4/F Building C, 2 Shangdi Xinxi Road

Relevant to this article

Synthesis and structure of cyclic phosphine-boranes

Doi:10.1016/S0022-328X(96)06616-8
(1997)
The First Tri- and Tetraalkoxysilanes with Four Different Substituents

Doi:10.1021/jo970317q
(1997)
Unexpected solvent/substitution-dependent inversion of the enantioselectivity in Michael addition reaction using chiral phase transfer catalysts

Doi:10.1016/j.tetlet.2015.07.074
(2015)
Six-membered bis(azaphosphorinane), readily available ligand for highly enantioselective asymmetric hydrogenations

Doi:10.1016/j.tetlet.2006.01.003
(2006)
Design, synthesis, and evaluation of the first mechanism-based inhibitor of glucosamine 6-phosphate synthase

Doi:10.1021/ja970254t
(1997)
Synthesis of furanose glycals from furanose 1,2-diols and their cyclic thiocarbonate esters

Doi:10.1016/S0008-6215(97)00072-4
(1997)

Article Doi