Synthesis and enzymatic hydrolysis of esters, constituting simple models of soft drugs

DOI: 10.1248/cpb.46.591

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 591 - 601 (1998)

Update date:2022-09-26

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Authors:

Graffner-Nordberg, Malin

Sjoedin, Karin

Tunek, Anders

Hallberg, Anders

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Article abstract of DOI:10.1248/cpb.46.591

One way to minimise systemic side effects of drugs is to design molecules, soft drugs, in such a way that they are metabolically inactivated rapidly after having acted on their pharmacological target. Hydrolases (esterases, peptidases, lipases, glycosidas

Full text of DOI:10.1248/cpb.46.591

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