Concise synthesis of L-α-phosphatidyl-D-myo-inositol 3,4-bisphosphate, an intracellular second messenger

Article abstract of DOI:10.1016/S0040-4039(97)00950-7

A highly efficient, asymmetric total synthesis of the title phospholipid as well as short chain diester and cross-linkable diether analogs was achieved in six steps from the readily available cyclitol 1.