Chemical and Pharmaceutical Bulletin p. 1120 - 1129 (1997)
Update date:2022-08-05
Topics:
Saito, Naoki
Tanitsu, Masa-Aki
Betsui, Tamaki
Suzuki, Rieko
Kubo, Akinori
(Z)-3-(2,4,5-Trimethoxy-3-methylbenzylidene)-1,6-dimethylpiperazine- 2,5-dione (7a) was prepared by a simple regioselective C-monomethylation of (Z)-4-(4-methoxybenzyl)-3-(2,4,5-trimethoxy-3-methylbenzylidene)-1- methylpiperazine-2,5-dione (3) followed by deprotection. Compound 7a was also prepared from (S)-1,4-diacetyl-3-methylpiperazine-2,5-dione (8) and the benzaldehyde derivative (9) in five steps as an optically active form. It was shown to be a useful intermediate for the preparation of novel octahydro- 1,5-imino-3-benzazocin-4,7,10-trione derivatives having a methyl group at the C-2 position, as ABC ring models of saframycins.
View MoreOren Hydrocarbons (Qingdao) Co., Ltd.
Contact:+86-532-68607667-801
Address:Room 3 # 302, No.9 Qingyun Road, Qingdao, China
Chemsky(shanghai)International Co.,Ltd.
Contact:0
Address:0
Shanghai Hanshare Industry Co.,Ltd.
Contact:86 21 20960688
Address:RM902-903,Building E, Wanda Plaza,No.26,Zhoukang Road, Pudong District, Shanghai, China
Lianyungang Ningkang Chemical Co., Ltd
Contact:.+86-518-88588008
Address:http://www.chemnk.com
Taizhou Chenyi chemical co. LTD,
Contact:13736652831
Address:NO.273 SHANGHAI SOUTH STREET,LUQIAO DISTRICT,ZHEJIANG PROVINCE,CHINA.
Doi:10.1021/ja210763n
(2012)Doi:10.1016/0022-328X(86)80013-4
(1986)Doi:10.1021/ja01608a018
(1955)Doi:10.1039/a606340c
(1997)Doi:10.1021/ja9715253
(1997)Doi:10.1002/ejoc.200700882
(2008)