Synlett p. 1013 - 1014 (1997)
Update date:2022-08-05
Topics:
Larsen, Scott D.
Exposure of 1H-pyrazole-1-alkanoic acids to two equivalents of n-butyllithium affords the corresponding cyclic ketones via a Parham-type cyclization process. Although yields are modest, this procedure represents a simple and direct intramolecular acylation of a non-nucleophilic pyrazole carbon.
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(1997)
