Bioorganic and Medicinal Chemistry Letters p. 2693 - 2698 (1996)
Update date:2022-08-05
Topics:
Dodd, Dharmpal S.
Shen, Zhongqi
Nishi, Takao
Graber, Norma
Bealls, Dawson
Fong, Miranda
Ebert, Tracy
2-Alkylsulfinyl-1,3,4-oxadiazoles have been identified as novel inhibitors of cell adhesion molecule expression on endothelial cells. These compounds have been shown to inhibit the up-regulation of ELAM-1 and VCAM-1 on activated human umbilical vein endothelial cells (HUVECs) as measured by ELISA.
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