Serine derived NK1 antagonists 2: A pharmacophore model for arylsulfonamide binding

DOI: 10.1016/S0960-894X(98)00319-9

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 1851 - 1856 (1998)

Update date:2022-08-05

Topics:

Authors:

Elliott Elliott

Broughton

Cascieri

Chicchi Chicchi

Huscroft

Kurtz Kurtz

MacLeod MacLeod

Sadowski

Stevenson

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0960-894X(98)00319-9

Modifications to the spirocyclic aryl sulfonamide portion of serine derived NK₁ antagonists allow a partial pharmacophore model to be developed.

Full text of DOI:10.1016/S0960-894X(98)00319-9

Products guided by the article

Product name:4-(2-tert-Butoxycarbonylamino-phenyl)-piperidine-1-carboxylic acid tert-butyl ester

Cas No:199105-02-7

R&D Labs maybe for 199105-02-7

MedicalChem(Yancheng)Manuf.Co.,Ltd.

Contact:+86-515-84383366

Address:Touzeng BinHai, YanCheng City, JiangSu Province, China
Xuzhou Tianrun Chemical Co.,Ltd

website:http://www.tianrunchem.cn

Contact:86-516-83832636

Address:fuxing road
Xi'an caijing Opto-Electrical Science & Technology Co., LTD

Contact:+86-29-88294447

Address:NO.168 Zhangba Rd. East, Xi'an, P.R.China
Nanjing Habo Medical Technology Co., Ltd.

Contact:025－85769882

Address:No.108. Ganjiabian east. Qixia District .Nanjing
Yixing Bluwat Chemicals Co., Ltd.

Contact:+86 510 87821568

Address:Yongan Road, Yixing Chemical Industrial Park, Yixing, Jiangsu, China

Relevant to this article

Unsymmetrically substituted bis(carbene)platinum(II) complexes

Doi:10.1016/S0022-328X(98)00937-1
(1999)
A highly enantioselective synthesis of cyclic α-amino acids involving a one-pot, single catalyst, tandem hydrogenation-hydroformylation sequence

Doi:10.1039/b200374k
(2002)
Host-guest interactions in nor-seco-cucurbit[10]uril: Novel guest-dependent molecular recognition and stereoisomerism

Doi:10.3762/bjoc.15.166
(2019)
Synthesis and anti-HIV-1 activity of novel 2,3-dihydro-7H-thiazolo[3,2- a]pyrimidin-7-ones

Doi:10.1021/jm970443m
(1998)
Doi:10.1139/v62-191
(1962)
2,3-Dimethyl-7-methoxy-6-aminoindole in the synthesis of linear pyrroloquinolines

Doi:10.1007/BF02290748
(1997)

Article Doi