Serine derived NK1 antagonists 2: A pharmacophore model for arylsulfonamide binding

DOI: 10.1016/S0960-894X(98)00319-9

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 1851 - 1856 (1998)

Update date:2022-08-05

Topics:

Authors:

Elliott Elliott

Broughton

Cascieri

Chicchi Chicchi

Huscroft

Kurtz Kurtz

MacLeod MacLeod

Sadowski

Stevenson

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0960-894X(98)00319-9

Modifications to the spirocyclic aryl sulfonamide portion of serine derived NK₁ antagonists allow a partial pharmacophore model to be developed.

Full text of DOI:10.1016/S0960-894X(98)00319-9

Products guided by the article

Product name:4-(2-tert-Butoxycarbonylamino-phenyl)-piperidine-1-carboxylic acid tert-butyl ester

Cas No:199105-02-7

R&D Labs maybe for 199105-02-7

Aqua Chem Industry Co., Ltd

Contact:+86-515-88356562

Address:No.2, West Daqing Road, Yancheng, Jiangsu, China
Jiaxing Carry Bio-Chem Technology Co.,Ltd

website:http://www.carrybiotech.com

Contact:0573-82788958

Address:Add.Fl 3th, Pharm Vally,Kaichuang Rd, Xiuzhou District, Jiaxing, Zhejiang,314031,China
Jiangsu Zhenfang Chemical CO.,LTD.(Suzhou Zhenfang Chemical Factory)

Contact:+86-512-69598882

Address:Room1201, Jiayuan Road No.1018, Xiangcheng District, Suzhou, China
Changsha Easchem Co.,Limited

website:http://www.easchem.com

Contact:+86-731-89722861 89722891

Address:2/F-4/Bld Colorful Palace, No.605 Changsha Ave, Yuhua Area Changsha Hunan China.
ZCIC INTERNATIONAL LTD

Contact:+86-512-56795332

Address:No227 Shuanglong Rd, Fenghuang, Zhangjiagang

Relevant to this article

Unsymmetrically substituted bis(carbene)platinum(II) complexes

Doi:10.1016/S0022-328X(98)00937-1
(1999)
A highly enantioselective synthesis of cyclic α-amino acids involving a one-pot, single catalyst, tandem hydrogenation-hydroformylation sequence

Doi:10.1039/b200374k
(2002)
Host-guest interactions in nor-seco-cucurbit[10]uril: Novel guest-dependent molecular recognition and stereoisomerism

Doi:10.3762/bjoc.15.166
(2019)
Synthesis and anti-HIV-1 activity of novel 2,3-dihydro-7H-thiazolo[3,2- a]pyrimidin-7-ones

Doi:10.1021/jm970443m
(1998)
Doi:10.1139/v62-191
(1962)
2,3-Dimethyl-7-methoxy-6-aminoindole in the synthesis of linear pyrroloquinolines

Doi:10.1007/BF02290748
(1997)

Article Doi