Y. Luo et al.
Publisher’s note: Springer Nature remains neutral with regard to
jurisdictional claims in published maps and institutional affiliations.
14. Barluenga S, Moulin E, Lopez P, Winssinger N. Solution‐ and
solid‐phase synthesis of radicicol (monorden) and pochonin C.
Chem – Eur J. 2005;11:4935–52.
15. Yamamoto K, Garbaccio RM, Stachel SJ, Solit DB, Chiosis G,
Rosen N, Danishefsky SJ. Total synthesis as a resource in the
discovery of potentially valuable antitumor agents: cyclopropar-
adicicol. Angew Chem Int Ed. 2003;42:1280–4.
16. Bai Y, Davis DC, Dai M. Natural product synthesis via palladium-
catalyzed carbonylation. J Org Chem. 2017;82:2319–28.
17. Ma K, Martin BS, Yin X, Dai M. Natural product syntheses via
carbonylative cyclizations. Nat Prod Rep. 2019;36:174–219.
18. Bai Y, Davis DC, Dai M. Synthesis of Tetrahydropyran/Tetra-
hydrofuran‐Containing Macrolides by Palladium‐Catalyzed
Alkoxycarbonylative Macrolactonizations. Angew Chem Int Ed.
2014;53:6519–22.
References
1. Oyama H, Sassa T, Ikeda M. Structures of new plant growth
inhibitors, trans-and cis-resorcylide. Agric Biol Chem.
1978;42:2407–9.
2. Barrow CJ. New macrocyclic lactones from a Penicillium species.
J Nat Prod. 1997;60:1023–5.
3. Delmotte P, Delmotte-Plaquee J. A new antifungal substance of
fungal origin. Nature. 1953;171:344.
4. Chiosis G, Lucas B, Huezo H, Solit D, Basso A, Rosen N.
Development of purine-scaffold small molecule inhibitors of
Hsp90. Curr Cancer Drug Tar. 2003;3:371–6.
19. Manoni F, Rumo C, Li L, Harran PG. Unconventional fragment
usage enables a concise total synthesis of (−)-callyspongiolide.
J Am Chem Soc. 2018;140:1280–4.
5. Xu L, Wu P, Xue J, Molnar I, Wei X. Antifungal and cytotoxic β-
resorcylic acid lactones from a paecilomyces species. J Nat Prod.
2017;80:2215–23.
20. Bai Y, Shen X, Li Y, Dai M. Total synthesis of (−)-spinosyn A
6. Couladouros EA, Mihou AP, Bouzas EA. First total synthesis of
trans-and cis-resorcylide: remarkable hydrogen-bond-controlled,
stereospecific ring-closing metathesis. Org Lett. 2004;6:977–80.
7. Mennen SM, Miller SJ. Development of a bio-inspired acyl-anion
equivalent macrocyclization and synthesis of a trans-resorcylide
precursor. J Org Chem. 2007;72:5260–9.
8. Takahashi T, Minami I, Tsuji J. Synthesis of dehydroxy-trans-
resorcylide by intramolecular alkylation of the protected cyano-
hydrin using a butadiene telomer as a building block. Tetrahedron
Lett. 1981;22:2651–4.
9. Lampilas M, Lett R. Convergent stereospecific total synthesis of
monochiral Monocillin I related macrolides. Tetrahedron Lett.
1992;33:773–6.
10. Lampilas M, Lett R. Convergent stereospecific total synthesis of
Monocillin I and Monorden (or Radicicol). Tetrahedron Lett.
1992;33:777–80.
via carbonylative macrolactonization.
2016;138:10838–41.
J Am Chem Soc.
21. Davis DC, Walker KL, Hu C, Zare RN, Waymouth RM, Dai M.
Catalytic carbonylative spirolactonization of hydro-
xycyclopropanols. J Am Chem Soc. 2016;138:10693–9.
22. Ma K, Yin X, Dai M. Total syntheses of bisdehydroneostemoninine
and bisdehydrostemoninine by catalytic carbonylative spir-
olactonization. Angew Chem Int Ed. 2018;57:15209–12.
23. Davis DC, Hoch DG, Wu L, Abegg D, Martin BS, Zhang Z,
Adibekian A, Dai M. Total synthesis, biological evaluation, and
target identification of rare abies sesquiterpenoids. J Am Chem
Soc. 2018;140:17465–73.
24. Gyorkos AC, Stille JK, Hegedus LS. The total synthesis of ( )-epi-
jatrophone and ( )-jatrophone using palladium-catalyzed carbo-
nylative coupling of vinyl triflates with vinyl stannanes as the
macrocycle-forming step. J Am Chem Soc. 1990;112:8465–72.
25. Houghton TJ, Choi S, Rawal VH. Efficient assembly of the
phomactin core via two different macrocyclization protocols. Org
Lett. 2001;3:3615–7.
11. Garbaccio RM, Stachel SJ, Baeschlin DK, Danishefsky SJ. Con-
cise asymmetric syntheses of radicicol and monocillin I. J Am
Chem Soc. 2001;123:10903–8.
12. Garbaccio RM, Danishefsky SJ. Efficient asymmetric synthesis of
radicicol dimethyl ether: a novel application of ring-forming olefin
metathesis. Org Lett. 2000;2:3127–9.
13. Geng X, Yang Z, Danishefsky SJ. Synthetic development of
radicicol and cycloproparadicicol: highly promising anticancer
agents targeting Hsp90. Synlett. 2004;8:1325–33.
26. Simon M, Karaghiosoff K, Knochel P. Diastereoselective intra-
molecular carbolithiations of stereodefined secondary alkyllithiums
bearing a remote alkynylsilane. Org Lett. 2018;20:3518–21.
27. Choe H, Cho H, Ko H, Lee J. Total synthesis of (+)-pochonin D
and (+)-monocillin II via chemo-and regioselective intramolecular
nitrile oxide cycloaddition. Org Lett. 2017;19:6004–7.