Bioorganic and Medicinal Chemistry Letters p. 41 - 46 (1998)
Update date:2022-08-02
Topics:
Cho, Won-Jea
Park, Myun-Ji
Chung, Byung-Ho
Lee, Chong-Ok
To investigate the structure-activity relationship of 7,8-dimethoxy-2-methyl-3-(4,5-methylenedioxy-2-vinylphenyl)isoquinolin-1(2H) -one 2, diverse substituted 3-arylisoquinolines were synthesized and tested in vitro antitumor activity against five human tumor cell lines. The results showed a broad antitumor spectrum for a series of 3-arylisoquinolines.
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Doi:10.1016/S0040-4039(98)00085-9
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(1998)Doi:10.1021/jacs.8b08100
(2018)Doi:10.1016/S0040-4020(02)00465-9
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(1990)
