Synthesis of a monocharged peptide nucleic acid (PNA) analog and its recognition as substrate by DNA polymerases

Article abstract of DOI:10.1080/15257779908043084

The preparation of a novel phosphoramidite monomer based on thyminyl acetic acid coupled to the secondary nitrogen of 2-(2-amino- ethylamino)ethanol is described. This monomer can be used to attach a deoxynucleotide to the carboxy terminus of a PNA oligom

Full text of DOI:10.1080/15257779908043084

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Nucleosides and Nucleotides
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Synthesis of a Monocharged Peptide
Nucleic Acid (PNA) Analog and Its
Recognition as Substrate by DNA
Polymerases
M. J. Lutz b , D. W. Will a , G. Breipohl a , S. A. Benner b & E.
Uhlmann a
a Hoechst Marion Roussel Deutschland GmbH, Chemical Research, G
838, D-65926, Frankfurt, Germany
b Swiss Federal Institute of Technology, Department of Chemistry,
CH-8092, Zürich, Switzerland
Version of record first published: 04 Oct 2006.
To cite this article: M. J. Lutz , D. W. Will , G. Breipohl , S. A. Benner & E. Uhlmann (1999): Synthesis
of a Monocharged Peptide Nucleic Acid (PNA) Analog and Its Recognition as Substrate by DNA
Polymerases, Nucleosides and Nucleotides, 18:3, 393-401
To link to this article: http://dx.doi.org/10.1080/15257779908043084
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