Preparation of fluorinated phenoxathiin dioxide monoamine oxidase-A inhibitors: Intramolecular radical substitution at sulfur versus the Mauthner synthesis

DOI: 10.1002/jhet.5570350332

Source and publish data:

Journal of Heterocyclic Chemistry p. 699 - 706 (1998)

Update date:2022-07-29

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Authors:

Boros, Eric E.

Hall, William R.

Harfenist, Morton

Kelley, James L.

Reeves, Mark D.

Styles, Virgil L.

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Article abstract of DOI:10.1002/jhet.5570350332

Five unique fluorinated analogs, 8a-c and 15a,b, of the monoamine oxidase-A inhibitor 3-iso-propoxyphenoxathiin 10,10-dioxide (II) were prepared via oxidation of the corresponding phenoxathiins 7 and 14. 3- Fluoro-7-isopropoxy- 7a, 2-fluoro-3-isopropoxy-

Full text of DOI:10.1002/jhet.5570350332

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