Novel route to the synthesis of hydroxylated pyrrolidine derivatives via the intramolecular reaction of γ-aminoallylstannane with aldehyde. Total synthesis of (+)-preussin

DOI: 10.3987/com-97-s19

Source and publish data:

Heterocycles p. 335 - 348 (1997)

Update date:2022-08-03

Topics:

Authors:

Kadota, Isao

Saya, Shioko

Yamamoto, Yoshinori

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.3987/com-97-s19

The thermal cyclization of γ-aminoallylstannane (8) having an aldehyde group gave β-hydroxypyrrolidine derivative (9a) as a sole product. This methodology was applied successfully to the total synthesis of (+)-preussin.

Full text of DOI:10.3987/com-97-s19

Products guided by the article

Product name:(S)-4-[2-(tert-Butyl-diphenyl-silanyloxy)-ethyl]-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester

Cas No:205491-15-2

R&D Labs maybe for 205491-15-2

APOLLO HEALTHCARE RESOURCES

Contact:+65 9658 0999

Address:26 Sin Ming Lane, Midview City, #05-118, Singapore 573971
Taizhou YOJOY Chemical Co., Ltd.

Contact:13857143241

Address:Yangfu Industrial Park, Xianju, Zhejiang, P. R. China
Shanghai Bojing Chemical Co., Ltd.

Contact:021-37122233

Address:6F Buildiing 11,No.388,Baifu Road,District Fengxian.Shanghai, China.
Shanghai Sungo Technology Chemical Co., Ltd

Contact:0086-21-51385579

Address:Room2010, F/20, Tonghua Plaza, NO 345 Jinxiang Road, Jinqiao Export Processing Zone, Shanghai, 201206 P.R.CHINA
JIANGXI XINXIN CHEMICAL CO., LTD.

Contact:86-15957176628

Address:INDUSTRY ROAD 1, INDUSTRIAL PARK, HEKOU TOWN,YANSHAN COUNTY, JIANGXI PROVINCE, CHINA

Relevant to this article

Investigation of the N-substituent conformation governing potency and μ receptor subtype-selectivity in (+)-(3R,4R)-dimethyl-4-(3- hydroxyphenyl)piperidine opioid antagonists

Doi:10.1021/jm980063g
(1998)
Different reactivity of the Ru-O bond in the chelated [(methoxyethyl)diphenylphosphine]ruthenium(II) complexes [(η⁶-C₆Me₆)Ru(P^∩O)X][BR ₄] in dependence on X = Cl and CH₃

Doi:10.1016/S0022-328X(97)00754-7
(1998)
(3-substituted benzyl)thiazolidine-2,4-diones as structurally new antihyperglycemic agents

Doi:10.1016/S0960-894X(99)00039-6
(1999)
Carboxylic acids and skeletal muscle chloride channel conductance: Effects on the biological activity induced by the introduction of methyl groups on the aromatic ring of chiral α-(4-chloro-phenoxy)alkanoic acids

Doi:10.1016/S0014-827X(01)01041-2
(2001)
1,1-bis(Methylthio)-2-Nitroethene in Superacids: NMR Study and Reactivity of the Formed Hydroxynitrillium Ion.

Doi:10.1016/0040-4020(95)00669-Y
(1995)
Doi:10.1016/S0008-6215(00)81427-5
(1968)

Article Doi