Novel route to the synthesis of hydroxylated pyrrolidine derivatives via the intramolecular reaction of γ-aminoallylstannane with aldehyde. Total synthesis of (+)-preussin

DOI: 10.3987/com-97-s19

Source and publish data:

Heterocycles p. 335 - 348 (1997)

Update date:2022-08-03

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Authors:

Kadota, Isao

Saya, Shioko

Yamamoto, Yoshinori

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Article abstract of DOI:10.3987/com-97-s19

The thermal cyclization of γ-aminoallylstannane (8) having an aldehyde group gave β-hydroxypyrrolidine derivative (9a) as a sole product. This methodology was applied successfully to the total synthesis of (+)-preussin.

Full text of DOI:10.3987/com-97-s19

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