Synthesis of some analogs of the methyl α-glycoside of the presumed antigenic determinant of the O-specific polysaccharide of Vibrio cholerae O:1, serotype ogawa

Article abstract of DOI:10.1080/07328309808002896

The following analogs of the title determinant, methyl 4,6-dideoxy-4-(3-deoxy-L-glycero-tetronamido)-2-O-methyl-α-D- mannopyranoside, have been prepared: methyl 3,4,6-trideoxy-4-(3-deoxy-L-glycero-tet ronamido)-2-O-methyl-α-D-mannopy ranoside, methyl 4,6-dideoxy -4-(4-hy droxybuty ramido)-2-O-methyl-α-D-mannopy ranoside, methyl 4,6-dideoxy -4-(3,4-dideoxy-L-glycero-tetronamido)-2-O-methyl-α-D-mannopyranoside, methyl 4,6-dideoxy -4-(3-deoxy -D-glycero-tetronamido)-2-O-methyl-α-D-mannopyranoside, methyl 4,6-dideoxy-4-(2-deoxy-L-glycero-tetronamido)-2-O-methyl-α-D- mannopyranoside, methyl 4-acetamido-4,6-dideoxy-2-O-methyl-α-D-mannopyranoside, methyl 4,6-dideoxy-4-(3-deoxy-L-glycero-tetronamido)-2-O-ethyl-α-D- mannopyranoside, and methyl 4,6-dideoxy-4-(3-deoxy-L-glycero-tetronamido)-2-O-propyl-α-D- mannopyranoside.