Tetrahedron Letters p. 3725 - 3728 (1998)
Update date:2022-08-03
Topics:
Moriguchi, Tomohisa
Yanagi, Terukazu
Wada, Takeshi
Sekine, Mitsuo
New aminoacyl-adenylate analogs (aa-AMPNs), in which the oxygen atom of the mixed anhydride bond of aminoacyl-adenylates is replaced by an NH group, were synthesized by the reaction of an adenosine 5'-phosphoramidite derivative with appropriately protected amino acid amides. Among various reagents studied for activation of the 5'-phosphoramidite derivative, 5-(4- nitrophenyl)-1H-tetrazole was found to give N-acyl phosphoramidate derivatives in good yields.
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Doi:10.1002/cber.19681011225
(1968)Doi:10.1039/a802183j
(1998)Doi:10.1021/jm970460b
(1998)Doi:10.1016/S0223-5234(98)80065-2
(1998)Doi:10.1111/0022-1082.00366
(1891)Doi:10.1016/S0040-4020(98)00298-1
(1998)
