Tetrahedron Letters p. 3927 - 3930 (1998)
Update date:2022-08-05
Topics:
Beecher, Jody E.
Tirrell, David A.
Protected derivatives of 3-pyrrolylalanine (3-PA) have been synthesized starting with N-tri(isopropyl)silylpyrrole. Following formylation and Boc protection, treatment with (±)-N-(benzyloxycarbonyl)-α-phosphonoglycine trimethyl ester provided a fully protected dehydro-3-pyrrolylalanine. Reduction of the double bond and removal of the methyl ester groups yielded 3-PA protected at the α- and pyrrole nitrogens. 3-PA is only transiently stable following N-deprotection.
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Doi:10.1016/S0022-328X(00)87672-X
(1968)Doi:10.1002/anie.201804249
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(2015)Doi:10.1002/jhet.5570350234
(1998)Doi:10.1055/s-1998-2071
(1998)Doi:10.1002/ejoc.201000406
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