Design and synthesis of isoxazole and isoxazoline linkage for replacement of nucleotide phosphodiester

DOI: 10.1016/S0960-894X(98)00210-8

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 1313 - 1316 (1998)

Update date:2022-08-05

Topics: Design and Synthesis Isoxazole Nucleotide Experimental Linkage isoxazoline

Authors:

Kim, Su Jeong

Lee, Ju Young

Kim, Byeang Hyean

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Article abstract of DOI:10.1016/S0960-894X(98)00210-8

Synthetic routes for oligonucleotides which have isoxazoline or isoxazole linkage have been developed, and di- and tri-nucleotides with thymine bases have been prepared.

Full text of DOI:10.1016/S0960-894X(98)00210-8

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