Bioorganic and Medicinal Chemistry Letters p. 1419 - 1424 (1998)
Update date:2022-08-03
Topics:
Bellier, Bruno
Da Nascimento, Sophie
Meudal, Herve
Gincel, Edith
Roques, Bernard P.
Garbay, Christiane
A new series of 4-substituted pipecolic acid derivatives was prepared and incorporated into dipeptoids. The resulting products behave as moderately potent CCK-B antagonists but their constrained structure and its comparison with structurally related compounds yield valuable information about the conformational requirements for optimal recognition of the CCK-B receptor by antagonists.
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Doi:10.1016/S0022-328X(98)00550-6
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(2001)Doi:10.1016/S0960-894X(98)00265-0
(1998)Doi:10.1055/s-1998-1755
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(1996)
