
Tetrahedron Letters p. 4513 - 4516 (1998)
Update date:2022-08-05
Topics:
Aoyagi, Sakae
Tanaka, Ryuta
Naruse, Masaichi
Kibayashi, Chihiro
An enantioselective approach to (-)-epibatidine based on asymmetric hetero Diels-Alder cycloaddition with an N-acylnitroso dienophile bearing 8- (2-naphthyl)menthol as a chiral source, wherein π-π stacking interaction between the naphthyl and nitrosocarbonyl groups may contribute to facial control, is described.
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