
Tetrahedron p. 9613 - 9622 (1998)
Update date:2022-08-04
Topics:
Brooks, Peter B.
Marson, Charles M.
Treatment of 3,4-epoxyamides with LDA affords γ-hydroxy-α,β- unsaturated amides, usually with high (E)-selectivity. The 3,4-epoxyamides were prepared by the epoxidation of β,γ-unsaturated amides with meta- chloroperbenzoic acid.
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