Segment-coupling Prins cyclizations

DOI: 10.1016/S0040-4039(98)01586-X

Source and publish data:

Tetrahedron Letters p. 7271 - 7274 (1998)

Update date:2022-07-29

Topics:

Authors:

Rychnovsky, Scott D.

Hu, Yueqing

Ellsworth, Bruce

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Article abstract of DOI:10.1016/S0040-4039(98)01586-X

A segment-coupling Prins cyclization was developed involving (1) esterification, (2) reductive acetylation and (3) Lewis acid promoted cyclization. A model for the bis-tetrahydropyran segment of phorboxazole was successful assembled using this new method.

Full text of DOI:10.1016/S0040-4039(98)01586-X

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