Effect on conformation on proton affinities of stereoisomeric ethers

Article abstract of DOI:10.1002/jms.1190300815

The proton affinity (PA) of cis-4-tert-butylcyclohexyl methyl ether with an axial methoxy group is higher by ~ 0.1 kcal mol^-1 (1 kcal = 4.184 kJ) than the trans isomer with the equatorial ether group. The gas-phase basicity shows a similar smal