A new synthetic approach towards α- and β-LNA (locked nucleic acids)

Article abstract of DOI:10.1080/15257779908041546

A bicyclo[2.2.1] phenyl thioglycoside was efficiently synthesised and introduced as the key synthon in a novel method for convergent synthesis of β-LNA-nucleosides as well as their α-configurated isomers. An acid-induced ring-opening reaction on the corre

Full text of DOI:10.1080/15257779908041546

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Nucleosides and Nucleotides
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A New Synthetic Approach Towards α-
and β-LNA (Locked Nucleic Acids)
Poul Nielsen a & Jesper Wengel b
a Department of Chemistry , Odense University , DK-5230, Odense M,
Denmark
b Center for Synthetic Bioorganic Chemistry, Department of
Chemistry , University of Copenhagen , Universitetsparken 5,
DK-2100, Copenhagen, Denmark
Published online: 04 Oct 2006.
To cite this article: Poul Nielsen & Jesper Wengel (1999) A New Synthetic Approach Towards
α- and β-LNA (Locked Nucleic Acids), Nucleosides and Nucleotides, 18:4-5, 701-702, DOI:
10.1080/15257779908041546
To link to this article: http://dx.doi.org/10.1080/15257779908041546
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