Tetrahedron Letters p. 9 - 12 (1999)
Update date:2022-08-03
Topics:
Burke, Steven D.
Letourneau, Jeffrey J.
Matulenko, Mark A.
The total synthesis of (+)-breynolide (2) is described. The primary focus is the synthesis of the advanced aldehyde intermediate 12, which comprises the cis-fused perhydrobenzothiophene ring system. Three stereoselectiye cyclohexene epoxidation/epoxide opening sequences and a glycolate ester Claisen rearrangement, by which all of the necessary oxygen functionality in 12 is introduced before installation of the thioether, are employed.
View MoreContact:+86-27-87204219, +86-27-87215023
Address:2402, HuiGu Space-time Building, 8 Forest Road, East Lake Hi-Tech Development Zone
Nantong Auxin Electronic Technology Co., LTD
Contact:86-513-88760026
Address:NO.5-1, Aoxin Road, Haian Hi-tech Development Zone, Jiangsu Province, China
Ceresking Ecology & Technology co.,ltd
Contact:86 22 66218397
Address:Room 1613, Zheshang Mansion, No. 1988, Yingbin Avenue, Binhai New District, Tianjin,China.
FUJIAN SHANSHUI CHEMICAL CORP.LTD.
Contact:+86-151-59920036
Address:Jinqiao Gareden, jo@fj-xinyi.com
website:http://www.dulynet.com/
Contact:025-84699383 -8003
Address:Room 503, Building 2, Chuangxinhui, No. 61 Wenjing Road, High-tech Development Zone, Pukou District, Nanjing City, Jiangsu Province Nanjing, Jiangsu
Doi:10.1002/(sici)1521-3765(19990104)5:1<274::aid-chem274>3.0.co;2-p
(1999)Doi:10.1016/S0022-328X(96)06725-3
(1997)Doi:10.1080/15257779908043070
(1999)Doi:10.1080/15257779908043064
(1999)Doi:10.1515/znb-1999-0108
(1999)Doi:10.1039/a808266i
(1999)
