Journal of Heterocyclic Chemistry p. 467 - 471 (1999)
Update date:2022-07-30
Topics:
Toche
Jachak
Sabnis
Kappe
A novel efficient synthesis of pyrano fused heterocycles namely, pyrano[3,2-c]quinoline-2,5(6H)-diones 3a-e, 7b-d, pyrano[3,2-c]benzopyran- 2,5(6H)-dione (7f), and pyrano[3,2-c]pyridine-2,5(6H)-diones 10, 11 was achieved by the condensation of 4-hydroxy-2-(1H)-quinolones 1a-e, 4- hydroxycoumarin (1f), or 4-hydroxy-2(1H)-pyridone (9) with α-acetyl-γ- butyrolactone (2) or the sodium salt of α-formyl-γ-butyrolactone (6), respectively, in the presence of ammonium acetate.
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(1999)Doi:10.1021/ja990819g
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